Case 1: Amira (39 years old)

Amira is a 39-year-old sports fanatic. In 5 years’ time, she has run 4 marathons and completed 1 triathlon. She was recently diagnosed with right-sided breast cancer.

Assessment summary

• Premenopausal
• No relevant medical history
• No family history of breast or ovarian cancer
• ECOG PS: 0
• Tumour size: cT1c, lymph node status: cN0
• Tumour biology: ER 0%, PgR 0%, HER2 IHC 0, Ki67 45%, G3, basal-like
• CT scan chest/abdomen and bone scan: cM0
• No BRCA germline mutation