Amy (79 years old)

Amy, 79 years old, was very passionate about her job as a secretary for her not-so-organised boss. She is retired now, but still helps her self-employed grandson, who is a plumber, with his administration.

She was diagnosed with metastatic bladder cancer during a workup for haematuria.

Assessment summary:

• Medical history: diabetes and diabetic nephropathy
• CT scan of chest, abdomen and pelvis: pelvic lymph node metastases and diffuse liver metastases
• Biopsy compatible with UCa
• ECOG PS: 1
• Peripheral neuropathy: grade 1 due to diabetes
• No hearing impairment
• GFR: 45 ml/min due to diabetic nephropathy
• Cardiac ejection fraction: 70%
• PD-L1 expression: strongly positive