Bladder cancer
First-line therapy of synchronous and metachronous metastatic UCaJude (70 years old)
Jude, 70 years old, has a profound passion for old-timer cars. His all-time favourite is the red Corvette from 1958 he fixed together with his best friend Jake.
Recently, he was diagnosed with metastatic UCa of the bladder.
Assessment summary:
- Medical history: diabetes and diabetic nephropathy
- CT scan of chest, abdomen and pelvis: diffuse liver and bone metastases
- ECOG PS: 1
- No peripheral neuropathy
- No hearing impairment
- GFR: 40 ml/min
- PD-L1 expression: low
The patient completed first-line treatment with gemcitabine + carboplatin with complete response but has developed significant neuropathy and fatigue.