Breast cancer
Adjuvant systemic treatment of luminal A/B early breast cancer in premenopausal womenZoya (48 years old)
Zoya is a 48-year-old audiologist who loves gardening and knitting during the weekends. She was diagnosed with early breast cancer following a screening mammography.
Assessment summary
- Premenopausal
- No relevant medical history
- No family history of breast or ovarian cancer
- Stage and tumour biology at diagnosis:
- cT1bN0M0
- ER 100%, PgR 100%, HER2 IHC 1+, Ki67 10%
- Upfront breast conserving surgery (BCS) + SLNB
- Pathology report:
- G1 invasive carcinoma of NST
- Unifocal, 12 mm, pT1c
- LVI and perineural invasion absent
- R0 resection (free margins)
- pN0 (0/3 sn)
- Multidisciplinary board meeting: postoperative RT and endocrine therapy